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JND3229

Cat. No. :YN340088

  • CAS No. :2260886-64-2

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    • Products Infomation
    • Biological Activity
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    • Product Name:JND3229
      CAS NO.:2260886-64-2
      Chemical Name:
      Synonyms:
      Molecular Weight:617.18
      Molecular Formula:C₃₃H₄₁ClN₈O₂
      SMILES:CC1=CC(NC2=NC(N([C@@H]3CC[C@@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:JND3229 is a highly potent and fourth-generation EGFRC797Sreversible inhibitor with IC50 value of 5.8nM, and also potently suppressed EGFRL858R/T790M and EGFRWTwith IC50 values of 30.5 and 6.8nM.
      IC50&Target:
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      Solvent & Solubility:
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