JND3229
Cat. No. :YN340088
CAS No. :2260886-64-2
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5mg
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Product Name: | JND3229 |
CAS NO.: | 2260886-64-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 617.18 |
Molecular Formula: | C₃₃H₄₁ClN₈O₂ |
SMILES: | CC1=CC(NC2=NC(N([C@@H]3CC[C@@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | JND3229 is a highly potent and fourth-generation EGFRC797Sreversible inhibitor with IC50 value of 5.8nM, and also potently suppressed EGFRL858R/T790M and EGFRWTwith IC50 values of 30.5 and 6.8nM. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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