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WZ-3146

Cat. No. :YN340090

  • CAS No. :1214265-56-1

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    • Products Infomation
    • Biological Activity
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    • Product Name:WZ-3146
      CAS NO.:1214265-56-1
      Chemical Name:
      Synonyms:
      Molecular Weight:464.95
      Molecular Formula:C₂₄H₂₅ClN₆O₂
      SMILES:CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM does not inhibit ERBB2 phosphorylation (T798I).
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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