WZ-3146
Cat. No. :YN340090
CAS No. :1214265-56-1
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5mg
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Product Name: | WZ-3146 |
CAS NO.: | 1214265-56-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 464.95 |
Molecular Formula: | C₂₄H₂₅ClN₆O₂ |
SMILES: | CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM does not inhibit ERBB2 phosphorylation (T798I). |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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