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Mavelertinib

Cat. No. :YN340119

  • CAS No. :1776112-90-3

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    • Product Name:Mavelertinib
      CAS NO.:1776112-90-3
      Chemical Name:
      Synonyms:
      Molecular Weight:415.42
      Molecular Formula:C₁₈H₂₂FN₉O₂
      SMILES:C=CC(N[C@@H]1CN(C2=NC(NC3=CN(C)N=C3OC)=C4N=CN(C)C4=N2)C[C@H]1F)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Mavelertinib is a selective, orally available and irreversibleEGFR tyrosine kinase inhibitor (EGFR TKI), with IC50s of 5, 4, 12 and 3nM for Del, L858R, and double mutants T790M/L858R and T790M/Del, respectively. Mavelertinib can be used for the research of non-small-cell lung cancer (NSCLC).
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