Mutated EGFR-IN-1
Cat. No. :YN340247
CAS No. :1421372-66-8
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order@ubiochem.com| Product Name: | Mutated EGFR-IN-1 |
| CAS NO.: | 1421372-66-8 |
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| Molecular Weight: | 445.56 |
| Molecular Formula: | C₂₅H₃₁N₇O |
| SMILES: | NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutatedEGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant. More information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer. |
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