RWJ-67657
Cat. No. :YN350162
CAS No. :215303-72-3
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5mg
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Product Name: | RWJ-67657 |
CAS NO.: | 215303-72-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 425.50 |
Molecular Formula: | C₂₇H₂₄FN₃O |
SMILES: | OCCC#CC1=NC(C2=CC=C(F)C=C2)=C(C3=CC=NC=C3)N1CCCC4=CC=CC=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor with IC50s of 1 and 11μM, respectively. RWJ-67657 displays no activity at p38γ and p38δ, and exhibits cardio protective effect. Anti-inflammatory and anti-tumor activity. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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