AL 8697
Cat. No. :YN350059
CAS No. :1057394-06-5
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order@ubiochem.com| Product Name: | AL 8697 |
| CAS NO.: | 1057394-06-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 402.41 |
| Molecular Formula: | C₂₁H₂₁F₃N₄O |
| SMILES: | O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AL 8697 is a specific and orally activep38α MAPKinhibitor with an IC50 of 6nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC50=82nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity. |
| IC50&Target: | |
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