YN320113 Silodosin 160970-54-7

Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.

YN322066 α1 adrenoceptor-MO-1 161905-64-2

α1 adrenoceptor-MO-1, an S enantiomer, has affinity atalpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.

YN320161 OPC-28326 167626-17-7

OPC-28326 is a selective peripheral vasodilator and an angatonist ofα2-adrenergic receptor, with Kiof 2040, 285, and 55 nM for α2A-, α2B- and α2C-adrenoceptors, respectively.

YN320133 RS 17053 hydrochloride 169505-93-5

RS 17053 hydrochloride is a potent and selectiveα1Aadrenoceptorantagonist, with apKivalue of 9.1 in native cell membrane and apA2value of 9.8 in functional assays.

YN320029 AGN 192836 171102-29-7

AGN 192836 is a potent and selectiveα2 adrenergicagonist with EC50s of 8.7, 41 and 6.6nM for α2A, α2B and α2C receptor, respectively.

YN320071 SR59230A 174689-39-5

SR59230A is a potent, selective, and blood-brain barrier penetratingβ3-adrenergic receptorantagonist with IC50s of 40, 408, and 648nM for β3, β1, and β2 receptors, respectively.

YN320970 Talibegron hydrochloride 178600-17-4

Talibegron hydrochloride (ZD2079 hydrochloride) is a potentβ3-adrenoceptoragonist with a pD2of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect.

YN320140 L-765314 189349-50-6

L-765314 is a potent and selectiveα1b adrenergic receptorantagonist with Kis of 5.4nM and 2.0nM for rat and human α1b adrenergic receptor, respectively.

YN322049 L-771688 200050-59-5

L-771688 is a highly selectiveα1A-Adrenoceptorantagonist with a Ki of 0.43±0.02nM.

YN320792 LY377604 204592-94-9

LY377604 is ahuman β3-adrenergic receptoragonist with an EC50 of 2.4nM and also aβ1- and β2-adrenergic receptorantagonist.

YN320051 Rilmenidine hemifumarate 207572-68-7

Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selectiveI1 imidazoline receptoragonist. Rilmenidine hemifumarate is analpha 2-adrenoceptoragonist. Rilmenidine hemifumarate induces autophagy. Rilmen...

YN322085 Fiduxosin 208993-54-8

Fiduxosin is a potentα1-adrenoceptorantagonist, with Kiof 0.160nM, 24.9nM, and 0.920nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.

YN322029 Lusaperidone 214548-46-6

Lusaperidone (R107474) is an α2adrenergic receptorantagonist with Kis of 0.13 and 0.15nM for α2A and α2C, respectively.

YN320507 Dabuzalgron 219311-44-1

Dabuzalgron (Ro 115-1240) is an orally active and selectiveα-1A adrenergic receptoragonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial functi...

YN320908 Mirabegron 223673-61-8

Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.

YN322077 AR-08 226081-74-9

AR-​08 is an agonist ofα2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD).

YN321223 Solabegron 252920-94-8

Solabegron (GW 427353) is a selectiveβ3-adrenergic receptoragonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22nM. Solabegron (GW 427353) is being develo...

YN320844 Indacaterol 312753-06-3

Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.

YN320744 Salmeterol-D3 497063-94-2

Salmeterol-D3 is the deuterium labeled Salmeterol (HY-14302). Salmeterol is a long-actingbeta2-adrenergic receptoragonist that is used for the study of asthma and chronic obstructive pulmonary disease (COPD).

YN320846 Vilanterol 503068-34-6

Vilanterol (GW642444) is a long-actingβ2-adrenoceptor(β2-AR) agonist with 24 h activity. ThepEC50s for β2-AR,β1-AR and β3-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.