YN320847 Vilanterol trifenatate 503070-58-4

Vilanterol trifenatate is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma.

YN321369 Carvedilol phosphate hemihydr... 610309-89-2

Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.

YN321140 Levalbuterol tartrate 661464-94-4

Levalbuterol HCl is a relatively selective beta2-adrenergic receptor agonist used for the treatment of asthma.

YN320671 Batefenterol 743461-65-6

Batefenterol (GSK961081, TD-5959) is both a muscarinic receptor antagonist and a β2-adrenoceptor agonist with Ki of 1.4 nM, 1.3 nM and 3.7 nM for hM2, hM3 muscarinic receptors and hβ2-adrenoceptor, respectively.

YN320845 Indacaterol maleate 753498-25-8

Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.

YN320930 Ulimorelin 842131-33-3

Ulimorelin (TZP-101) is aghrelin receptor (GRLN)agonist with an EC50 of 29nM and a Ki of 16nM. Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action atα1-adrenoceptors. Ulimorel...

YN321088 Centanafadine hydrochloride 923981-14-0

Centanafadine (hydrochloride) is dualnorepinephrine (NE)/dopamine (DA)transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6nM, 38nM and 83nM for human NE, DA and serotonin transporter , respectively.

YN321388 Doxazosin D8 1126848-44-9

Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274). Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1 adrenergic receptors.

YN320247 SR59230A hydrochloride 1135278-41-9

SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetratingβ3-adrenergic receptorantagonist with IC50s of 40, 408, and 648nM for β3, β1, and β2 receptors, respectively.

YN321481 Naftopidil hydrochloride 1164469-60-6

Naftopidil hydrochloride (KT-611 hydrochloride) is a selectivealpha1-adrenoceptorantagonist, with antiproliferative effects. Naftopidil dihydrochloride can be used for the research of prostate hyperplasia.

YN320074 Clenproperol-D7 1173021-09-4

Clenproperol-D7 is the deuterium labeled Clenproperol. Clenproperol is a β2-adrenergic agonist.

YN320749 ADRA1D receptor agonist 1 1191908-14-1

ADRA1D receptor agonist 1 (compound (R)-9S) is a potent, selective and orally activeα1Dadrenoceptorantagonist, with a Ki of 1.6nM.

YN320545 BI-167107 1202235-68-4

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constantKdof 84 pM.

YN321401 Ivabradine D3 Hydrochloride 1217809-61-4

Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new Ifinhibitor with IC50 of 2.9μM, and used as a pure heart rate lowering agent.

YN321343 Zilpaterol-d7 1217818-36-4

Zilpaterol-d7 is a deuterium labeled Zilpaterol. Zilpaterol is aβ-adrenergic receptoragonist that putatively, through activation of protein kinase A, increases protein synthesis in skeletal muscle fibers as well as reduces lipogenesis ...

YN320063 4-Hydroxypropranolol D7 hydr... 1219804-03-1

4-Hydroxypropranolol D7 hydrochloride ((±)-4-hydroxy Propranolol D7 hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency com...

YN320089 Cimaterol-D7 1228182-44-2

Cimaterol-D7 is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to incre...

YN320692 Cimbuterol-D9 1246819-04-4

Cimbuterol-D9 is the deuterium labeled Cimbuterol. Cimbuterol is aβ-adrenergic agonist.

YN320726 Mabuterol-D9 1246819-58-8

Mabuterol-D9 is a deuterium labeled Mabuterol. Mabuterol is an agonist of theβ2-adrenergic receptor.

YN321499 Sotalol D6 hydrochloride 1246820-85-8

Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitiveβ-adrenergic receptorantagonist that also exhibits Class III antiarrhythmic properties by its inhibition ofp...