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Ponatinib

Cat. No. :YN440187

  • CAS No. :943319-70-8

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    • Products Infomation
    • Biological Activity
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    • Product Name:Ponatinib
      CAS NO.:943319-70-8
      Chemical Name:
      Synonyms:
      Molecular Weight:532.56
      Molecular Formula:C₂₉H₂₇F₃N₆O
      SMILES:CC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37nM, 1.1nM, 1.5nM, 2.2nM, and 5.4nM forAbl,PDGFRα,VEGFR2,FGFR1, and Src, respectively.
      IC50&Target:
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      Solvent & Solubility:
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