AST 487
Cat. No. :YN440307
CAS No. :630124-46-8
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order@ubiochem.com| Product Name: | AST 487 |
| CAS NO.: | 630124-46-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 529.56 |
| Molecular Formula: | C₂₆H₃₀F₃N₇O₂ |
| SMILES: | O=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AST-487,a N,N'-diphenyl urea,is an ATP competitive inhibitor of Flt3 with ki of 0.12 μM.Besides FLT3, AST487 also inhibits RET,KDR,c-KIT,and c-ABL kinase with IC50 values below 1 μM. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
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