Bafetinib
Cat. No. :YN440406
CAS No. :859212-16-1
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order@ubiochem.com| Product Name: | Bafetinib |
| CAS NO.: | 859212-16-1 |
| Chemical Name: | |
| Synonyms: | NS-187 |
| Molecular Weight: | 576.62 |
| Molecular Formula: | C₃₀H₃₁F₃N₈O |
| SMILES: | O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19 nM in cell-free assays, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit. Phase 2. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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