GZD856
Cat. No. :YN440033
CAS No. :1257628-64-0
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order@ubiochem.com| Product Name: | GZD856 |
| CAS NO.: | 1257628-64-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 532.56 |
| Molecular Formula: | C₂₉H₂₇F₃N₆O |
| SMILES: | O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(C#CC4=CN5C(N=C4)=CC=N5)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | GZD856 is a potent and orally bioavailablePDGFRα/βinhibitor with IC50s of 68.6 and 136.6nM, respectively.GZD856 is also aBcr-AblT315Iinhibitor with IC50s of 19.9 and 15.4 nM for Bcr-Abl and T315I mutant. Antitumor activity. |
| IC50&Target: | |
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| Solvent & Solubility: | |
| References: |
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