Rebastinib
Cat. No. :YN440241
CAS No. :1020172-07-9
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Product Name: | Rebastinib |
CAS NO.: | 1020172-07-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 553.59 |
Molecular Formula: | C₃₀H₂₈FN₇O₃ |
SMILES: | CC(C)(C)C1=NN(C(NC(NC2=C(F)C=C(OC3=CC(C(NC)=O)=NC=C3)C=C2)=O)=C1)C4=CC=C5C(C=CC=N5)=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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