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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320794 Norepinephrine hydrochloride 329-56-6

    Norepinephrine hydrochloride (Levarterenol hydrochloride) is aβ1-selectiveadrenergic receptoragonist withEC50of 5.37μM.

  • YN320209 Prostaglandin E2 363-24-6

    Prostaglandin E2 palys important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.

  • YN360852 Diazoxide 364-98-7

    Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.

  • YN482072 Xanthinol Nicotinate 437-74-1

    Xanthinol Nicotinate is a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose metabolism resulting in an increased energy.

  • YN481985 Timonacic 444-27-9

    Timonacic is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.

  • YN481986 Cyclandelate 456-59-7

    Cyclandelate is an effective inhibitor of rat hepatic acycloenzyme A: cholesterol acyltransferase (ACAT) with IC50 of 80 μM.

  • YN420297 α-Linolenic acid 463-40-1

    α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation ofPI3K/Aktsignaling. α-Linolenic acid possess...

  • YN360995 Marinobufogenin 470-42-8

    Marinobufogenin is a strong inhibitor ofNa+/K+ATPasethat has been identified in mammalian plasma.

  • YN481109 Sandaracopimaric acid 471-74-9

    S and aracopimaric acid is a diterpenoid with anti-inflammatory effect. S and aracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93μM.

  • YN373081 Stachydrine 471-87-4

    Stachydrine, also known as N,N-dimethylproline or proline betaine, is a quaternary ammonium derivative of proline that occurs widely in Medicago species. It is an osmoprotective compound found in urine.

  • YN330558 Ruscogenin 472-11-7

    Ruscogenin has been found to exert significant anti-inflammatory and anti-thrombotic activities; the possible mechanism of the anti-inflammatory activity is role of intercellular adhesion molecule-1 and nuclear factor-kappaB. Ruscogen...

  • YN330499 Astaxanthin 472-61-7

    Astaxanthin, a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability.

  • YN483305 Veratrosine 475-00-3

    Veratramine is a steroidal alkaloid extracted from the roots and rhizomes of Veratrum californicum.

  • YN350235 Isorhamnetin 480-19-3

    Isorhamnetin on experimental IBD via PXR-mediated up-regulation of xenobiotic metabolism and down-regulation of NF-κB signaling. Isorhamnetin is efficacious in protecting hepatocytes against oxidative stress by Nrf2 activation ...

  • YN481706 Eugenin 480-34-2

    Eugenin is a chromone isolated fromPeucedanum japonicum, with potent antiplatelet aggregation activity.

  • YN270537 Osajin 482-53-1

    Osajin is the major bioactive isoflavone present in the fruit ofMaclura pomiferawith antitumor, antioxidant and anti-inflammatory activities.

  • YN321740 Ajmalicine 483-04-5

    Ajmalicine (Raubasine) is found in herbs of Catharanthus roseus, is an antihypertensive drug used in the treatment of high blood pressure, decreases peripheral resistance and blood pressure. Ajmalicine (Raubasine) is an adrenolytic d...

  • YN360958 Dihydroberberine 483-15-8

    Dihydroberberine inhibitshuman ether-a-go-go-related gene (hERG)channels and remarkably reducesheat shock protein 90 (Hsp90)expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic,...

  • YN373123 Toddalolactone 483-90-9

    Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 20 min prior to substrate addition measured after 20 min by Ellman's method

  • YN321706 Osthole 484-12-8

    Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.

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