YN350229 Corynoxeine 630-94-4

Corynoxeine, which could be isolated from Uncaria rhynchophylla, is a useful and prospective compound in the prevention and treatment for vascular diseases. It is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC ...

YN360870 Clopamide 636-54-4

Clopamide is categorised as a thiazide-like diuretic and works in similar way as the thiazide diuretics do.

YN483081 Dracorhodin 643-56-1

Dracorhodin, the main component in sanguis draconis, is a flavylium compound belonging to the anthocyanin family. Dracorhodin can induce vasodilatation.

YN280120 Isosorbide 652-67-5

Isosorbide is a heterocyclic compound that is derived from glucose, used as a diuretic.

YN410032 Gossypin 652-78-8

Gossypin is a flavone isolated fromHibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, analgesic and hepatoprotective activities. Gossypin inhibitsNF-κB and NF-κB-regulated gene ...

YN420283 Metformin 657-24-9

Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin indu...

YN251491 L-Lysine hydrochloride 657-27-2

L-Lysine hydrochloride is an essential amino acid. It is often added to animal feed used as a dietary supplement and plays a major role in calcium absorption, building muscle protein, recovering from surgery or sports injuries, and the b...

YN330712 Metyrosine 672-87-7

Metyrosine is a selectivetyrosine hydroxylase enzymeinhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood p...

YN360941 Oxypeucedanin 737-52-0

Oxypeucedanin is a furocoumarin derivative isolated fromAngelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits thehKv1.5 currentwith an IC50 value of 76nM. Oxypeucedanin prolongs cardiac action potential du...

YN484295 DL-m-Tyrosine 775-06-4

DL-m-Tyrosine shows effects onArabidopsisroot growth. Carbidopa combination with DL-m-tyrosine shows a potent hypotensive effect.

YN310027 AS8351 796-42-9

AS-8351 is a histone demethylase inhibitor that could induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.

YN420290 Cyclovirobuxine D 860-79-7

Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicineBuxus microphylla. Cyclovirobuxine D inducesautophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits ...

YN321433 L-(-)-α-Methyldopa hydrochl... 884-39-9

L-(-)-α-Methyldopa (MK-351) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective forα2-adrenergic receptors). L-(-)-α-Methyldopa hydrochloride is a prodrug and is metabolized (alpha-Methylepi...

YN350253 Enniatin B 917-13-5

Enniatin B is aFusariummycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 113μM in an enzyme assay using rat liver microsomes. Enniatins B decreases the activation ofERK(...

YN321498 Sotalol hydrochloride 959-24-0

Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.

YN321655 Moxisylyte hydrochloride 964-52-3

Moxisylyte hydrochloride is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.

YN372917 Canrenone 976-71-6

Canrenone, a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascit...

YN360844 Meticrane 1084-65-7

Meticrane is a diuretic. Meticrane inhibits the reabsorption ofsodium and chlorideions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.

YN480135 Guancydine 1113-10-6

Guancydine (Guancidine) is an antihypertensive agent.

YN420251 Metformin hydrochloride 1115-70-4

Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).