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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN372217 Fluvastatin 93957-54-1

    Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent ant...

  • YN372218 Fluvastatin sodium 93957-55-2

    Fluvastatin Sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.

  • YN372221 (3S,5R)-Fluvastatin sodium 94061-81-1

    (3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8nM. Fluvastatin protects vascular...

  • YN370073 (±)-Equol 94105-90-5

    (±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.

  • YN330620 Piceatannol 3'-O-glucoside 94356-26-0

    Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelialnitric oxide(NO)synthasethrough inhibition of arginase activity with IC50s of 11.22 µM and 11.06 µM againstarginase I and arginase II, respecti...

  • YN321583 Nadolol D9 94513-92-5

    Nadolol D9 (SQ-11725 D9) is the deuterium labeled Nadolol. Nadolol is a non-selective and orally activeβ-adrenergic receptorsblocker.

  • YN360478 Levcromakalim 94535-50-9

    Levcromakalim ((-)-Cromakalim) is an ATP-sensitiveK+channel(KATP) activator.

  • YN360687 Lemildipine 94739-29-4

    Lemildipine is a new dihydropyridinecalciumentry blocker.

  • YN290516 Gypenoside XLIX 94987-08-3

    Gypenoside XLIX, a dammarane-type glycoside, is a prominent component ofG. pentaphyllum. Gypenoside XLIX is a selectiveperoxisome proliferator-activated receptor (PPAR)-alphaactivator and inhibits cytokine-induced vascular...

  • YN321371 (R)-Carvedilol 95093-99-5

    (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selectiveβ/α-1blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).

  • YN321370 (S)-Carvedilol 95094-00-1

    (S)-Carvedilol, the S-enantiomer of Carvedilol, is a non-selectiveβ/α-1blocker. (S)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).

  • YN360757 Ranolazine 95635-55-5

    Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.

  • YN360617 Ranolazine dihydrochloride 95635-56-6

    Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.

  • YN360400 Desethylamiodarone hydrochlor... 96027-74-6

    Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition ...

  • YN322030 Nuvenzepine 96487-37-5

    Nuvenzepine is anmAChRantagonist, has the potential for gastrospasm treatment.

  • YN360230 Palonidipine 96515-73-0

    Palonidipine is acalciumantagonist which is potential for the therapy of angina-pectoris and hypertension .

  • YN482371 Lappaconitine hydrobromide 97792-45-5

    Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.

  • YN370189 Senazodan 98326-32-0

    Senazodan is a Ca2+sensitiser, and also shows inhibition effect onPDE III.

  • YN321153 Metoprolol Succinate 98418-47-4

    Metoprolol Succinate is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.

  • YN360524 (S)-(-)-Bay-K-8644 98625-26-4

    (S)-(-)-Bay-K-8644 is an agonist of L-typeCa2+channel. (S)-(-)-Bay-K-8644 activates Ba2+currents (IBa) (EC50=32nM).

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