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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN480312 Lucidenic acid D 98665-16-8

    Lucidenic acid D (Lucidenic acid D2), isolated from the gills ofGanoderma lucidum, is a highly oxidized lanostane-type triterpenoid.

  • YN360804 Ropivacaine hydrochloride 98717-15-8

    Ropivacaine hydrochloride is a potentsodium channelblocker and blocks impulse conduction via reversible inhibition ofsodium ion influxin nerve fibrese. Ropivacaine is also an inhibitor of K2P(two-pore domain potassium channel)TREK...

  • YN360525 (R)-(+)-Bay-K-8644 98791-67-4

    (R)-(+)-Bay-K-8644 is acalcium channelinhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+currents (IBa) (IC50=975nM).

  • YN361069 McN5691 99254-95-2

    McN5691 is a voltage-sensitivecalcium channelblocker.

  • YN270093 BTZO-1 99420-15-2

    BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apo...

  • YN480580 Serelaxin 99489-94-8

    Serelaxin (RLX-030), a recombinant form of human gene-2 relaxin targeting theRLN receptor, is a vasoactive peptide hormone with an antifibrotic activity .

  • YN360688 Pranidipine 99522-79-9

    Pranidipine is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.

  • YN483856 Neuropeptide FF 99566-27-5

    Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the b...

  • YN360816 Lercanidipine 100427-26-7

    Lercanidipine is a vasoselective dihydropyridine calcium antagonist used for the treatment of essential hypertension.

  • YN330689 Pamicogrel 101001-34-7

    Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregatory properties.

  • YN373969 Desethyl KBT-3022 101001-72-3

    Desethyl KBT-3022 is the main active metabolite of the new antiplatelet agent, KBT-3022.

  • YN361102 OR-1855 101328-85-2

    OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.

  • YN321962 β-CGRP, human 101462-82-2

    β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1nM and 300nM for CRLR...

  • YN360088 Sematilide hydrochloride 101526-62-9

    Sematilide hydrochloride (CK-1752 hydrochloride) is a selectiveIKrchannel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifierK+current(IC50=25μM). Sematilide is a class III antiarrhythmic ...

  • YN360087 Sematilide 101526-83-4

    Sematilide (CK-1752) is a selectiveIKrchannel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifierK+current(IC50=25μM). Sematilide is a class III antiarrhythmic agent.

  • YN1570001 DPCPX 102146-07-6

    DPCPX (PD 116948), a xanthine derivative, is a highly potent and selectiveAdenosine A1 receptorantagonist, with aKiof 0.46nM in 3H-CHA binding to A1 receptors in rat whole brain membranes .

  • YN483717 Kushenol N 102490-65-3

    Kushenol N is a prenylated flavonoid that can be isolated from the root ofSophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities.

  • YN370182 Saterinone hydrochloride 102685-83-6

    Saterinone hydrochloride is aphosphodiesterase III(PDE III) inhibitor.

  • YN483802 [Glu1]-Fibrinopeptide B 103213-49-6

    [Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), mo...

  • YN330428 Lacidipine 103890-78-4

    Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.

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