YN360667 SM-6586 103898-38-0

SM-6586 is acalcium channelantagonist and inhibitor of Na+/H+ and Na+/Ca2+exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.

YN373753 Angiotensinogen (1-14), human 104180-23-6

Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides.

YN280135 Typhaneoside 104472-68-6

Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.

YN360182 Barnidipine 104713-75-9

Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [^3...

YN480036 TA-7552 104756-72-1

TA-7552 is a potent cholesterol-lowering agent.

YN360181 Barnidipine hydrochloride 104757-53-1

Barnidipine hydrochloride (Mepirodipine hydrochloride) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21nMol/l), has selective action against CaA receptors. Barnidipine hydro...

YN371600 Cinacalcet metabolite M4 104774-87-0

Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease.

YN450086 Hydroxyfasudil 105628-72-6

Hydroxyfasudil is aROCKinhibitor, with IC50s of 0.73 and 0.72μM forROCK1 and ROCK2, respectively.

YN320134 CGP 20712 A 105737-62-0

CGP 20712 A (CGP 20712 mesylate) is a highly selectiveβ1-adrenoceptorantagonist with an IC50 of 0.7nM. CGP 20712 A exhibits ~10,000-fold selectivity over β2-adrenoceptors.

YN372188 Olprinone 106730-54-5

Olprinone(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.

YN480332 GYY4137 106740-09-4

GYY4137 is a slow releasingH2S donorwith vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity .

YN372736 Perindopril erbumine 107133-36-8

Perindopril Erbumine is a potent ACE inhibitor with IC50 of 1.05 nM.

YN481815 (S)-Propafenone 107381-32-8

(S)-Propafenone ((S)-SA-79) is the S-enantiomer of Propafenone. (S)-Propafenone ((S)-SA-79) exerts beta-blocking action and the sodium channel-dependent antiarrhythmic class 1 activity.

YN372768 Eplerenone 107724-20-9

Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.

YN320795 Norepinephrine bitartrate mon... 108341-18-0

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.

YN482985 Ilexsaponin A 108524-93-2

Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury throughanti-apoptoticpathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST...

YN361062 YS-201 108852-42-2

YS-201 is a dihydropyridine-typecalcium channelantagonist. YS-201 has the potential for angina pectoris and hypertension treatment.

YN373350 Ilexsaponin B2 108906-69-0

Ilexsaponin B2 is a saponin isolated from the root ofIlex pubescensHook. et Arn. Ilexsaponin B2 is a potentphosphodiesterase 5 (PDE5) and PDEIinhibitor with IC50 values of 48.8μM and 477.5μM, respectively.

YN483228 Ilexoside D 109008-27-7

Ilexoside D is isolated from the roots ofIlex pubescens Hook. et Arn. Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity.

YN370186 Utibapril 109683-61-6

Utibapril is anangiotensin-converting enzyme (ACE)inhibitor with antihypertensive activities.