Torin 2
Cat. No. :YN420146
CAS No. :1223001-51-1
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order@ubiochem.com| Product Name: | Torin 2 |
| CAS NO.: | 1223001-51-1 |
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| Molecular Weight: | 432.40 |
| Molecular Formula: | C₂₄H₁₅F₃N₄O |
| SMILES: | O=C1N(C2=C(C=C1)C=NC3=CC=C(C=C32)C4=CC=C(N=C4)N)C5=CC=CC(C(F)(F)F)=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53?/? MEFs cell line 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively. |
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