PIK-75 hydrochloride
Cat. No. :YN420158
CAS No. :372196-77-5
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Product Name: | PIK-75 hydrochloride |
CAS NO.: | 372196-77-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 488.74 |
Molecular Formula: | C₁₆H₁₅BrClN₅O₄S |
SMILES: | BrC(C=C1)=CN2C1=NC=C2/C=N/N(S(=O)(C3=C(C=CC([N+]([O-])=O)=C3)C)=O)C.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays. |
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References: |
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