Compound 401
Cat. No. :YN420261
CAS No. :168425-64-7
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5mg
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Product Name: | Compound 401 |
CAS NO.: | 168425-64-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 281.31 |
Molecular Formula: | C₁₆H₁₅N₃O₂ |
SMILES: | O=C1C=C(N2CCOCC2)N=C3N1C=CC4=C3C=CC=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Compound 401 is a synthetic inhibitor of DNA-PK and mTOR (IC50=5.3 μM). It has no inhibition on p110α/p85α PI3K (>100 μM) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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