PI-103 Hydrochloride
Cat. No. :YN420022
CAS No. :371935-79-4
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Product Name: | PI-103 Hydrochloride |
CAS NO.: | 371935-79-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 384.82 |
Molecular Formula: | C₁₉H₁₇ClN₄O₃ |
SMILES: | OC1=CC(C2=NC3=C(OC4=C3C=CC=N4)C(N5CCOCC5)=N2)=CC=C1.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PI-103 Hydrochloride is a dualPI3K and mTORinhibitor with IC50s of 8nM, 88nM, 48nM, 150nM, 20nM, and 83nM forp110α,p110β,p110δ,p110γ,mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PKwith an IC50 of 2nM. PI-103 Hydrochloride inducesautophagy. |
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