YN322073 CI-949 104961-19-5

CI-949 is an allergic mediator release inhibitor, which inhibitshistamine,leukotriene C4/D4(LTC4/LTD4), and thromboxane B2(TXB2)release with IC50s of 11.4μM, 0.5μM and 0.1μM, respectively.

YN321800 Senktide 106128-89-6

Senktide is a tachykininNK3receptoragonist.

YN321553 Tamsulosin 106133-20-4

Tamsulosin is a selective α1 receptor antagonist that has preferential selectivity for the α1A receptor in the prostate versus the α1B receptor in the blood vessels.

YN321841 DAPTA 106362-34-9

DAPTA is a water soluble potent, selective CCR5 antagonist which potently inhibits specific CD4-dependent binding of gp120 Bal (IC50 = 0.06 nM) and CM235 (IC50 = 0.32 nM) to CCR5.

YN322056 Falintolol, (Z)- 106401-52-9

Falintolol, (Z)-, a newβ-adrenergicantagonist, is characterized by the presence of an oxime function.

YN321554 Tamsulosin hydrochloride 106463-17-6

Tamsulosin (Flomax) hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.

YN321694 Loxiglumide 107097-80-3

Loxiglumide is a cholecystokinin (CCK-1) receptor antagonist.

YN481282 Exemestane 107868-30-4

Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.

YN251714 KT5720 108068-98-0

KT5720 is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor ofprotein kinase A (PKA), with a Ki of 60nM.

YN320795 Norepinephrine bitartrate mon... 108341-18-0

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.

YN322050 FRG8701 108498-50-6

FRG-8701 is a newHistamine H2-receptorantagonist with an IC50 of ranging from 0.25 to 0.43μM.

YN321404 Mizolastine 108612-45-9

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Mizolastine is a histamine H1-receptor antagonist with IC50...

YN321549 Epinastine hydrochloride 108929-04-0

Epinastine is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.

YN321467 (S)-Terazosin 109351-33-9

(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinityα-adrenoceptorantagonist with Ki values of 3.91nM, 0.79nM and 1.16nM forα1a,α1b and α1d-adrenoceptor, respectively. (S)-Ter...

YN321466 (R)-Terazosin 109351-34-0

(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potentα1-adrenoceptorantagonist with Ki values of 6.51nM, 1.01nM and 1.97nM forα1a,α1b and α1d-adrenoceptor, respectively.

YN320048 Plerixafor 110078-46-1

Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.

YN440440 Secretin, canine 110786-77-1

Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Sr...

YN321834 [Sar9,Met(O2)11]-Substance... 110880-55-2

[Sar9,Met(O2)11]-Substance P is atachykinin NK1receptorselective agonist.

YN321576 Seratrodast 112665-43-7

Seratrodast is a potent and selective thromboxane A2 receptor (TP) antagonist with IC50 of 40 nM used primarily in the treatment of asthma and used as anti-inflammatory agent.

YN321967 Scyliorhinin II 112748-19-3

Scyliorhinin II is a selectiveneurokinin-3 receptoragonist, with a Ki of 2.5nM for neurokinin-3 receptor in rat cerebral cortex.