YN320201 Wy 49051 113418-56-7

Wy 49051 is a potent, orally activeH1 receptorantagonist, with IC50 of 44nM.

YN321703 Baohuoside I 113558-15-9

Baohuoside I (also known as Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.

YN321156 Losartan 114798-26-4

Losartan D4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

YN330249 AhR modulator-1 115039-00-4

AhR modulator-1 (compound 6-MCDF) is a selective and orally activearyl hydrocarbon receptor (AhR)modulator. AhR modulator-1 inhibits metastasis, in part, by inhibitingprostatic VEGFproduction prior to tumor formation. AhR ...

YN320763 Detomidine carboxylic acid 115664-39-6

Detomidine carboxylic acid is the major urinary metabolite of Detomidine. Detomidine is a syntheticα2-adrenergicagonist and an animal analgesic sedative. Detomidine also has cardiac and respiratory effects and an antidiuretic act...

YN321476 Levobetaxolol hydrochloride 116209-55-3

Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.

YN321570 Ramatroban 116649-85-5

Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.

YN380115 (+)-Phenserine 116839-68-0

(+)-Phenserine is a novel selectivecholinesterasenoncompetitive inhibitor with an IC50 of 45.3μM.

YN321807 Endothelin 1 (swine, human) 117399-94-7

Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB.

YN321398 Lafutidine 118288-08-7

Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.

YN321426 Nebivolol 118457-14-0

Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.

YN321951 Peptide YY (PYY), human 118997-30-1

Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through theNeuropeptide Y receptors.

YN321980 Neuropeptide Y (22-36) 119019-65-7

Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.

YN361015 Cyclic ADP-​ribose 119340-53-3

Cyclic ADP-ribose (cADPR) is a potent second messenger forcalcium mobilizationthat is synthesized from NAD+by a ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly byRyanodine receptor-mediated relea...

YN321853 Galanin (1-30), human 119418-04-1

Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist ofGalR1 and GalR2 receptors, with Kis of both 1nM.

YN320663 Dexloxiglumide 119817-90-2

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8).

YN483970 Protein Kinase C Peptide S... 120253-69-2

Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled recep...

YN483722 Protirelin Acetate 120876-23-5

Protirelin (Thyrotropin-releasing-hormone, TRH, Thyroliberin) acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory function...

YN320248 Amibegron hydrochloride 121524-09-2

Amibegron hydrochloride is a selectiveβ3-adrenoceptoragonist, with an EC50 of 3.5nM forβ-adrenoceptorin rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity.

YN321840 [bAla8]-Neurokinin A(4-10) 122063-01-8

[bAla8]-Neurokinin A(4-10) is aneurokinin 2 (NK2) receptoragonist.