YN320221 PD 123319 130663-39-7

PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.

YN320939 Fuscoside 131631-89-5

Fuscoside (OPC-21268) is an orally effective, nonpeptide,vasopressin V1receptor antagonist with an IC50 of 0.4μM.

YN320996 YS-49 132836-42-1

YS-49 is aPI3K/Akt(a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibitsangiotensin II (Ang II)-stimulated proliferation of VSMCs via induct...

YN321241 BIBS 39 133085-33-3

BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.

YN321861 GR-73632 133156-06-6

GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.

YN321888 Men 10376 135306-85-3

Men 10376 is a selectivetachykinin NK-2 receptorantagonist, with a Ki of 4.4μM for rat small intestine NK-2 receptor.

YN320184 CGP48369 135689-23-5

CGP48369 is a nonpeptidicangiotensin II receptorantagonist, used for anti-hypertensive research.

YN320582 BQ-123 136553-81-6

BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.

YN320222 PD 123319 ditrifluoroacetate 136676-91-0

PD 123319 (ditrifluoroacetate) is a potent, selectiveAT2 angiotensin II receptorantagonist with IC50 of 34nM.

YN322082 CCK-A receptor inhibitor 1 137004-80-9

CCK-A receptor inhibitor 1 is acholecystokinin A(CCK-A)receptorinhibitor with a bingingIC50 of 340nM.

YN320024 2-(E-2-decenoylamino)ethyl 2-... 137089-36-2

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostagl and in E2 in ulcerated rats induced by water im...

YN321180 Valsartan 137862-53-4

Valsartan is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure.

YN321183 Mozavaptan 137975-06-5

Mozavaptan is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.

YN321424 Irbesartan 138402-11-6

Irbesartan (SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

YN320578 Mozavaptan hydrochloride 138470-70-9

Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine derivative and a potent, selective, competitive and orally activevasopressin V2receptorantagonist with an IC50 of 14nM. Mozavaptan hydrochloride shows ~85-fold...

YN321827 Galantide 138579-66-5

Galantide, a non-specificgalanin receptorantagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1nM and ~6nM) in the rat hypothalamus. Galanti...

YN320146 Darbufelone 139226-28-1

Darbufelone is a dual inhibitor of cellularPGF2α and LTB4production. Darbufelone potently inhibitsPGHS-2(IC50= 0.19μM) but is much less potent withPGHS-1(IC50=20μM).

YN320147 Darbufelone mesylate 139340-56-0

Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellularPGF2α and LTB4production. Darbufelone potently inhibitsPGHS-2(IC50= 0.19μM) but is much less potent withPGHS-1(IC50= 20μM).

YN321428 Candesartan 139481-59-7

Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.

YN370971 Lodenafil 139755-85-4

Lodenafil is a potentphosphodiesterase type 5 (PDE5)inhibitor for the treatment of erectile dysfunction (ED).