KB02-SLF
Cat. No. :YN330229
CAS No. :2384184-40-9
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5mg
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Product Name: | KB02-SLF |
CAS NO.: | 2384184-40-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 949.52 |
Molecular Formula: | C₅₀H₆₅ClN₄O₁₂ |
SMILES: | O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCOCCOCCNC(COC3=CC4=C(N(C(CCl)=O)CCC4)C=C3)=O)=O)=C2)CCC5=CC=C(OC)C(OC)=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | KB02-SLF is a PROTAC-based nuclearFKBP12degrader (molecular glue). KB02-SLF promotes nuclearFKBP12degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase lig and KB02 via a linker to form KB02-SLF. |
IC50&Target: | |
In Vitro: | |
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Clinical Trial: | |
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References: |
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