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KB02-SLF

Cat. No. :YN330229

  • CAS No. :2384184-40-9

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    • Products Infomation
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    • Product Name:KB02-SLF
      CAS NO.:2384184-40-9
      Chemical Name:
      Synonyms:
      Molecular Weight:949.52
      Molecular Formula:C₅₀H₆₅ClN₄O₁₂
      SMILES:O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCOCCOCCNC(COC3=CC4=C(N(C(CCl)=O)CCC4)C=C3)=O)=O)=C2)CCC5=CC=C(OC)C(OC)=C5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:KB02-SLF is a PROTAC-based nuclearFKBP12degrader (molecular glue). KB02-SLF promotes nuclearFKBP12degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase lig and KB02 via a linker to form KB02-SLF.
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