Rapamycin-d3
Cat. No. :YN330059
CAS No. :392711-19-2
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Product Name: | Rapamycin-d3 |
CAS NO.: | 392711-19-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 917.19 |
Molecular Formula: | C₅₁H₇₆D₃NO₁₃ |
SMILES: | O=C([C@@]1(O[C@@H](CC[C@H]1C)C[C@@H](/C(C)=C/C=C/C=C/[C@H](C2)C)OC([2H])([2H])[2H])O)C(N3[C@@H](CCCC3)C(O[C@@H](CC([C@@H](/C=C([C@H]([C@H](C([C@@H]2C)=O)OC)O)C)C)=O)[C@@H](C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Rapamycin-d3 (Sirolimus-d3) is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant. |
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Clinical Trial: | |
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References: |
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