FKBP12 PROTAC dTAG-13
Cat. No. :YN330142
CAS No. :2064175-41-1
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Product Name: | FKBP12 PROTAC dTAG-13 |
CAS NO.: | 2064175-41-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 1049.17 |
Molecular Formula: | C₅₇H₆₈N₄O₁₅ |
SMILES: | COC1=CC=C(CC[C@H](C2=C(OCC(NCCCCCCOC3=CC=CC4=C3C(N(C5CCC(NC5=O)=O)C4=O)=O)=O)C=CC=C2)OC([C@@H]6CCCCN6C([C@@H](CC)C7=CC(OC)=C(OC)C(OC)=C7)=O)=O)C=C1OC |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader. FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader ofFKBP12F36Vwith expression of FKBP12F36Vin-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activatorBRD4by bridging BET bromodomains to an E3 ubiquitin ligase CRBN. |
IC50&Target: | |
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References: |
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