YN321398 Lafutidine 118288-08-7

Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.

YN321701 Bepotastine 125602-71-3

Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease.

YN321584 Levocetirizine 130018-77-8

Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.

YN322101 Levocetirizine dihydrochlorid... 130018-87-0

Levocetirizine is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.

YN321492 Olopatadine hydrochloride 140462-76-6

Olopatadine HCl is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.

YN320328 Iodophenpropit dihydrobromide 145196-87-8

Iodophenpropit dihydrobromide is a potent and selectivehistamine H3 receptorantagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD0.32nM).

YN320110 Clobenpropit dihydrobromide 145231-35-2

Clobenpropit dihydrobromide is a potenthistamine H3Rantagonist/inverse agonist with apEC50of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist athistamine H4receptors (Ki13nM). Clobenpropit dihydrobro...

YN321110 Alcaftadine 147084-10-4

Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.

YN321579 Fexofenadine hydrochloride 153439-40-8

Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.

YN320190 ReN-1869 hydrochloride 170149-76-5

ReN 1869 hydrochloride is a novel, selectivehistamine H1receptorantagonist, which demonstrates affinity to the histamine H1receptor (guinea pig brain) with Kiof 0.19±0.04μM and the non-selective σ site (guinea pig brain) with Ki...

YN321661 Acrivastine D7 172165-56-9

Acrivastine D7 (BW825C D7) is a deuterium labeled Acrivastine. Acrivastine is a short acting histamine 1 receptor antagonist.

YN320745 Rupatadine Fumarate 182349-12-8

Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.

YN320893 Ciproxifan 184025-18-1

Ciproxifan (FUB 359) is a potent, selective, orally bioavailable and competitive antagonist ofhistamine H3-receptor, with an IC50 of 9.2nM. Ciproxifan displays low apparent affinity at other receptor subtypes. Ciproxifan can be ...

YN320960 Ciproxifan maleate 184025-19-2

Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.

YN321326 Bepotastine besilate 190786-44-8

Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.

YN320871 Bilastine 202189-78-4

Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine and has a rapid onset and prolonged duration of action.

YN320310 Cipralisant 213027-19-1

Cipralisant is a potent and selectivehistamine H3 receptorantagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47nM for rat histamine H3 receptor; Cipralisant has the potential...

YN320158 Bamirastine 215529-47-8

Bamirastine inhibits lig and binding to recombinant human histamine H1receptors (rhH1R) with an IC50 value of 17.3nM.

YN320069 Cetirizine Impurity D 346451-15-8

Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamineH1-receptorantagonist. Cetirizine marks antiallergic properties and inhibits...

YN321564 Doxepin D3 Hydrochloride 347840-07-7

Doxepin D3 Hydrochloride is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selectivehistamine receptor H1antagonist. Doxepin hy...