YN320925 Bavisant dihydrochloride hydr... 1103522-80-0

Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for A...

YN321341 Doxylamine D5 1173020-59-1

Doxylamine D5 is deuterium labeled Doxylamine.

YN320106 Tesmilifene fumarate 1185241-83-1

Tesmilifene fumarate (DPPE fumarate), an H1C receptorantagonist, potentiates a wide range of cytotoxics and even to offer some protection of normal cells.

YN321608 Cinnarizine D8 1185242-27-6

Cinnarizine D8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.

YN321532 Hydroxyzine D8 1189480-47-4

Hydroxyzine D8 is deuterium labeled Hydroxyzine. Hydroxyzine is ahistamine H1-receptorantagonist.

YN321226 (±)-Methotrimeprazine (D6) 1189805-51-3

(±)-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.

YN321342 Doxylamine D5 succinate 1216840-94-6

Doxylamine D5 succinate is deuterium labeled Doxylamine, which is a first generation antihistamine.

YN321115 Cetirizine D4 1219803-84-5

Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamineH1-receptorantagonist. Cetirizine...

YN322067 H3 receptor-MO-1 1240914-03-7

H3 receptor-MO-1 is a modulator ofhistamine H3 receptor.

YN320655 LML134 1542135-76-1

LML134 (compound 18b) is an orally active and high selectiveHistamine 3 receptor (H3R)inverse agonist with Kis of 0.3nM and 12nM for hH3R cAMP and hH3R bdg. LML134 penetrates the brain rapidly, leading to high H3R...

YN320327 ROS 234 dioxalate 1781941-93-2

ROS 234 dioxalate is a potentH3antagonist, with apKBof 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and aED50of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diox...

YN321111 Alcaftadine-D3 1794775-80-6

Alcaftadine-D3 (R89674-D3) is a deuterium labeled Alcaftadine. Alcaftadine (HY-17039) is a H1 histamine receptor antagonist.

YN320746 Rupatadine D4 fumarate 1795153-63-7

Rupatadine D4 fumarate (UR-12592 D4 fumarate) is a deuterium labeled Rupatadine fumarate. Rupatadine Fumarate (UR-12592 Fumarate) is a potent dualPAF/H1antagonist with Kiof 0.55/0.1μM(rabbit platelet membranes/guinea pig c...

YN321531 Hydroxyzine D4 2070014-84-3

Hydroxyzine D4 is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclichistamine H1-receptorantagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties.

YN321114 Cetirizine D8 dihydrochlorid... 2070015-04-0

Cetirizine D8 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamineH1-receptorantagon...

YN321239 Adriforant hydrochloride 2096455-90-0

Adriforant hydrochloride (PF-3893787 hydrochloride) is a novelhistamine H4 receptorantagonist binding affinity (Ki=2.4nM) and is also a functional (Ki=1.56nM) antagonist.

YN321643 Chloropyramine hydrochloride

Chloropyramine hydrochloride is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.