YN320560 Pitolisant 362665-56-3

Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant humanhistamine H3 receptor(Ki=0.16nM).

YN320561 Pitolisant oxalate 362665-57-4

Pitolisant oxalate is a potent and selective nonimidazole inverse agonist at the recombinant humanhistamine H3 receptor(Ki=0.16nM).

YN320558 JNJ-5207852 398473-34-2

JNJ-5207852 is a selective and potenthistamine H3receptor (H3R) antagonist, withpKisof 8.9, 9.24 for rat and human H3R, respectively.

YN320741 JNJ-7777120 459168-41-3

JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.

YN320559 ABT-239 460746-46-7

ABT-239 is a novel, highly efficacious, non-imidazole class ofH3Rantagonist and a transient receptor potential vanilloid type 1 (TRPV1) antagonist.

YN321580 Fexofenadine D6 548783-71-7

Fexofenadine D6 (MDL-16455 D6) is deuterium labeled is Fexofenadine, which is an antihistamine pharmaceutical agent.

YN322021 SUN 1334H 607736-84-5

SUN 1334H is a potent, orally active, highly selectiveH1 receptorantagonist, with Kiof 9.7nM.

YN320817 GSK189254A 720690-73-3

GSK189254A (GSK189254) is a novel, potent and selective histamineH3receptor antagonist with pKi values. of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.

YN321116 Cetirizine D8 774596-22-4

Cetirizine D8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamineH1-receptorantagonist. Cetirizine...

YN320472 H4 Receptor antagonist 1 848217-00-5

H4 Receptor antagonist 1 is a potent and selectivehistamine H4 receptorinverse agonist, with an IC50 of 19nM.

YN322020 MK-0249 862309-06-6

MK-0249 is a potenthistamine H3 receptorantagonist, with Kiof 1.7nM for human H3.

YN320269 S 38093 862896-30-8

S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.

YN320096 (R)-(-)-α-Methylhistamine d... 868698-49-1

(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective H3 histaminereceptor agonist with aKdof 50.3nM. (R)-(-)-α-Methylhistamine dihydrobromide can cross the blood-brain barrier, and can enhance memory retention, at...

YN320562 Pitolisant hydrochloride 903576-44-3

Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant humanhistamine H3 receptor(Ki=0.16nM).

YN321777 Psoralenoside 905954-17-8

Psoralenoside is a benzofuran glycoside fromPsoralea corylifolia. Psoralenoside exhibits high binding affinities againsthistaminergic H1,calmodulin, and voltage-gated L-typecalcium channels(E-value≥-6.5 Kcal/mol). Psoralenoside ...

YN320587 PF-03654764 935840-35-0

PF-03654764 is an orally active, selective histamineH3receptor antagonist with Ki values of 1.2nM and 7.9nM for human H3 and rat H3in whole cell assay, respectively. The combination of PF-03654764 and Fexofenadine (HY-B0...

YN320145 VUF10460 1028327-66-3

VUF10460 is a non-imidazole histamineH4receptor agonist; binds to rat H4 receptor with a pKi of 7.46.

YN320421 PF-03654746 Tosylate 1039399-17-1

PF-03654746 Tosylate is a potent and selectivehistamine H3 receptorantagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human c...

YN320107 JNJ-39758979 1046447-90-8

JNJ-39758979 is a selective, orally active, and high-affinityhistamine H4receptorantagonist with Kis of 12.5, 5.3, and 25nM for human, mouse, and monkey histamine H4receptor, respectively. JNJ-39758979 functionally antagoniz...

YN321405 Mizolastine dihydrochloride 1056596-82-7

Mizolastine dihydrochloride is a histamine H1-receptor antagonist with IC50 of 47nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Mizolastine is a histamine H1-receptor antago...