YN360971 Methyllycaconitine citrate 351344-10-0

Methyllycaconitine citrate is a specific antagonist ofα7 neuronal nicotinic acetylcholine receptor(α7nAChR).

YN250601 Delafloxacin meglumine 352458-37-8

Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.

YN310228 SIRT1-IN-1 352554-02-0

SIRT1-IN-1 is a selectiveSIRT1inhibitor with an IC50 of 0.205μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5μM. SIRT1-IN-1, a indole, is acytomegalovirus (CMV)inhibitors and has antiviral activity.

YN482997 Caesalmin B 352658-23-2

Caesalmin B is a furanoditerpenoid lactone isolated fromCaesalpinia minax. Caesalmin B exhibits antiviral activity.

YN480906 Desbutyl Lumefantrine 355841-11-1

Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.

YN371749 T-705RMP 356783-08-9

T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC50 of 601μM.

YN250498 T-705RTP sodium 356783-10-3

T-705RTP sodium is a selective and GTP-competitiveinfluenza virus RNA polymeraseinhibitor with an IC50 of 0.14μM and a Ki of 1.52μM. T-705RTP sodium is the active triphosphate metabolite of T-705 and has potent a...

YN250580 BMS-378806 357263-13-9

BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

YN250939 Doripenem monohydrate 364622-82-2

Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.

YN420154 YM-201636 371942-69-7

YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue).

YN251857 Human β-defensin-2 372146-20-8

Human β-defensin-2 (HβD-2) is a small cysteine-rich cationicskin-antimicrobial peptide (SAP)produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and C and ida, bu...

YN251866 rCRAMP (rat) 376364-38-4

rCRAMP (rat) is the rat cathelin-related antimicrobial peptide. rCRAMP (rat) contributes to the antibacterial activity in rat brain peptide/protein extracts. rCRAMP (rat) is a potential key player in the innate immune system ...

YN250621 Tenofovir alafenamide 379270-37-8

Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.

YN250622 Tenofovir alafenamide fumarat... 379270-38-9

Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcr...