YN250053 ST-193 489416-12-8

ST-193 is a potent broad-spectrumarenavirusinhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1nM, respectively.

YN320926 Cenicriviroc 497223-25-3

Cenicriviroc (CVC, TAK-652, TBR-652) is a potent, orally active dual inhibitor of CC chemokine receptor 2 (CCR2) and CCR5. Cenicriviroc also inhibits HIV-1 and HIV-2 with potent anti-inflammatory and antiinfective a...

YN320927 Cenicriviroc Mesylate 497223-28-6

Cenicriviroc Mesylate (TAK-652 Mesylate) is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity.

YN250788 D77 497836-10-9

D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).

YN480720 Cyclopyrimorate 499231-24-2

Cyclopyrimorate, a highly effective bleaching herbicide for weed control in rice fields, targetshomogentisate solanesyltransferase (HST). HST is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) b...

YN250121 Rilpivirine 500287-72-9

Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.

YN250617 SQ109 502487-67-4

SQ109 is a potent inhibitor of thetrypomastigoteform of the parasite, with IC50for cell killing of 50±8nM. SQ109, targetsMmpL3, is an antitubercular agent.

YN250101 Ac-CoA Synthase Inhibitor... 508186-14-9

ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).

YN370279 Raltegravir 518048-05-0

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several...

YN251839 Influenza HA (307-319) 528526-85-4

Influenza HA (307-319) is 13 amino acids 307 to 319 fragment of Influenza HA. Influenza HA is a glycoprotein found on the surface of influenza viruses.

YN330005 PF-4878691 532959-63-0

PF-4878691 (3M-852A) is a potent, orally active, and selectiveToll-like receptor 7 (TLR7)agonist modelled to dissociate its antiviral and inflammatory activities.

YN340233 Tofacitinib citrate 540737-29-9

Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively.

YN371227 HIV-1 integrase inhibitor 544467-07-4

HIV-1 integrase inhibitor is uesful for anti-HIV.

YN330456 Dapsone D8 557794-38-4

Dapsone D8 is a deuterium labeled Dapsone. Dapsone is a potent, blood-brain penetrant and orally activeantibiotic, has bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone is used for dermatologic disorder resea...

YN321274 Mavorixafor 558447-26-0

Mavorixafor (AMD-070) is a potent, selective and orally availableCXCR4antagonist, with an IC50 value of 13nM against CXCR4125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in M...

YN250542 A2ti-1 570390-00-0

A2ti-1 is a selective and high-affinityannexin A2/S100A10 heterotetramer (A2t)inhibitor with an IC50 of 24μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents hu...

YN290177 ML-60218 577784-91-9

ML-60218 is a broad-spectrumRNA pol IIIinhibitor, with IC50s of 32 and 27μM forSaccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and to hamper the formation of new ones without the need f...

YN250425 2',5-Difluoro-2'-deoxycytidin... 581772-30-7

2',5-Difluoro-2'-deoxycytidine, compound 13, has potent anti-HCVactivity and toxicity to ribosomal RNA (rRNA).

YN321125 Vicriviroc maleate 599179-03-0

Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist ofCCR5, with a Ki of 2.5nM, and also inhibits HIV-1 in PBMC cells, withIC90s of 3.3n...

YN251880 SP187 615253-61-7

SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.