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Inflammation/Immunology

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN270534 Dihydrokaempferol 480-20-6

    Dihydrokaempferol is isolated fromBauhinia championii(Benth). Dihydrokaempferol inducesapoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good c and idate for new antiarthritic drugs.

  • YN373253 Pinostrobin 480-37-5

    Pinostrobin is a flavonoid can be found in many plants, and has anti-oxidant, anti-inflammatory, anti-cancer and neuroprotective properties. Pinostrobin is a potentPCSK9inhibitor and inhibits the catalytic activity of PCSK...

  • YN251502 Pinocembrin 480-39-7

    Pinocembrin is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and a...

  • YN330520 Naringenin 480-41-1

    Naringenin is a natural predominant flavanone derived from plant food, which is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune s...

  • YN251699 Filipin III 480-49-9

    Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolideantifungal antibioticproduced byS. filipinensis,S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration o...

  • YN482602 Ginkgetin 481-46-9

    Ginkgetin is a natural biflavonoid isolated from leaves of Ginkgo biloba L; effects of anti-inflammation and anticancer have been reported. IC50 value:

  • YN251734 Cepharanthine 481-49-2

    Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.

  • YN380218 Tangeretin 481-53-8

    Tangeretin, a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities.

  • YN251529 Isopimpinellin 482-27-9

    Isopimpinellin and imperatorin have chemopreventive effects when administered orally on skin tumor initiation by 7,12-dimethylbenz[a]anthracene (DMBA). Isopimpinellin effectively inhibits mouse COH activity (IC50 values 19-40 mic...

  • YN330609 Isoquercetin 482-35-9

    Isoquercitrin, a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.

  • YN251487 Hyperoside 482-36-0

    Hyperoside, a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.

  • YN251558 Afzelin 482-39-3

    Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found inHouttuynia cordataThunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. A...

  • YN482548 Isobergapten 482-48-4

    Isobergapten is an allelopathic inhibitor isolated from seeds ofHevacleum laciniatum.

  • YN270537 Osajin 482-53-1

    Osajin is the major bioactive isoflavone present in the fruit ofMaclura pomiferawith antitumor, antioxidant and anti-inflammatory activities.

  • YN360958 Dihydroberberine 483-15-8

    Dihydroberberine inhibitshuman ether-a-go-go-related gene (hERG)channels and remarkably reducesheat shock protein 90 (Hsp90)expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic,...

  • YN321732 Jatrorrhizine hydroxide 483-43-2

    Jatrorrhizine hydroxide is an alkaloid isolated fromCoptis chinensiswith neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor ofAChE(IC50=872...

  • YN330624 Sphondin 483-66-9

    Sphondin, isolated fromHeracleum laciniatum, possesses an inhibitory effect on IL-1β-induced increase in the level ofCOX-2protein and PGE2release in A549 cells.

  • YN483052 Calycanthoside 483-91-0

    Calycanthoside is a natural compound isolated fromAngelica tenuissima.

  • YN321706 Osthole 484-12-8

    Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.

  • YN330639 Okanin 484-76-4

    Okanin, effective constituent of the flower teaCoreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of theTLR4/NF-κBsignaling pathways.

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