YN340269 Reticuline 485-19-8

Reticuline, isolated fromLitsea cubeba, shows anti-inflammatory effects throughJAK2/STAT3 and NF-κBsignaling pathways. Reticuline inhibits mRNA expressions of TNF-α, and IL-6 and reduces the phosphorylation level...

YN330580 Isofraxidin 486-21-5

Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/ Isofraxidin has definite anti-ba...

YN310343 Daphnetin 486-35-1

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activi...

YN483604 Isoformononetin 486-63-5

Isoformononetin is an analog of Daidzein (HY-N0019) and hasimmunoprotectiveeffects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions...

YN481989 Dipyrocetyl 486-79-3

Dipyrocetyl is an anti-inflammatory and analgesic agent extracted from patent WO 2011132171 A1.

YN360927 N-Methylcytisine 486-86-2

N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective lig and of nicotinic receptors of acetylcholine in the central ne...

YN373119 Phillyrin 487-41-2

Forsythin (FOR) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.

YN373023 Icariin 489-32-7

Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.

YN480630 α-Truxillic acid 490-20-0

α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities.

YN480393 β-Tocotrienol 490-23-3

β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol.

YN330508 (-)-Epicatechin 490-46-0

(?)Epicatechin is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has insulin mimic action and improves heart health.

YN350270 2,5-Dihydroxyacetophenone 490-78-8

2,5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and...

YN482231 Thymoquinone 490-91-5

Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects.

YN251941 4(3H)-Quinazolinone 491-36-1

Some 4-quinazolinone derivatives have antiplatelet activity.

YN373062 Luteolin 491-70-3

Luteolin is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 &muM, 6.4 &muM, 13.9 &muM, 11.1 &muM and 9.5 &muM, respectively. Phase 2.

YN483008 Iridin 491-74-7

Iridin is an isoflavone isolated fromIris milesii.

YN483273 (-)-Butin 492-14-8

(-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood ofDalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.

YN360051 Kynurenic acid 492-27-3

Kynurenic acid, a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist It proved to be an antagonist at NMDA, kainate and AMPA receptors.

YN373285 Auraptene 495-02-3

Auraptene is the most abundant naturally occurring geranyloxycoumarin. Auraptene is primarily isolated from plants in the Rutaceae family, such ascitrusfruits. Auraptene decreases the secretion of matrix metalloproteinase 2 (MMP-2) a...

YN380236 Nodakenin 495-31-8

Nodakenin is a compound with anti-allergic and anti-inflammatory activities.