YN321516 Fluocinonide 356-12-7

Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.

YN320755 Betamethasone 378-44-9

Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

YN481607 Desoximetasone 382-67-2

Desoximetasone is a synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity.

YN321685 Fluorometholone 426-13-1

Fluorometholone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.

YN321754 (-)-Curine 436-05-5

(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated fromChondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition ofpr...

YN270523 Diffractaic acid 436-32-8

Diffractaic acid, a major constituent ofU. longissimi, acts as an effective proapoptotic agent in various disorders research. Diffractaic acid is the analgesic and antipyretic component ofUsnea diffracta.

YN251525 Genkwanin 437-64-9

Genkwanin exerts its anti-inflammatory effect mainly through the regulation of the miR-101/MKP-1/MAPK pathway. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms...

YN483281 Gentianine 439-89-4

Gentianine, an active metabolite of Swertiamarin, has anti-diabetic effect and anti-inflammatory property.

YN321266 Clemizole 442-52-4

Clemizole, a first-generation histamine receptor (H1) antagonist, is a potent inhibitor of behavioural and electrographic seizure activity. It has a potential therapeutic effect on hepatitis C infection and also potently inhibits...

YN270422 Azathioprine 446-86-6

Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.

YN251332 Ethoxzolamide 452-35-7

Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with K_i of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectivel...

YN482946 Coniferaldehyde 458-36-6

Growth inhibition of human A549 cells by Sulforhodamine B assay

YN360946 (+)-Borneol 464-43-7

(+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.

YN251449 Asiatic acid 464-92-6

Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.

YN330632 Arjunolic acid 465-00-9

Arjunolic acid is a saponin isolated fromSymplocos lancifolia and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potentantioxidant and pl...

YN482665 Hecogenin 467-55-0

Hecogenin is a steroid saponin isolated fromAgave sisalana and is a selective inhibitor ofhuman UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and ...

YN450143 Jervine 469-59-0

Jervine is a Hedgehog signaling (IC50=500-700 nM) inhibitor that inhibits the sonic hedgehog (shh) pathway by interacting with smoothened.

YN330638 Cafestol 469-83-0

Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is aERKinhibitor for AP-1-targeted activity againstPGE2production and the mRNA expression ofcyclooxygenase (COX)-2in LPS-act...

YN361014 1,4-Cineole 470-67-7

1,4-Cineole is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both humanTRPM8 and humanTRPA1.

YN373068 18β-Glycyrrhetinic acid 471-53-4

Enoxolone is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.