Ruxolitinib
Cat. No. :YN340236
CAS No. :941678-49-5
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order@ubiochem.com| Product Name: | Ruxolitinib |
| CAS NO.: | 941678-49-5 |
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| Molecular Weight: | 306.37 |
| Molecular Formula: | C₁₇H₁₈N₆ |
| SMILES: | N#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ruxolitinib (INCB18424) is a potent and selectiveJAK1/2inhibitor with IC50s of 3.3nM and 2.8nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib inducesautophagy and kills tumor cells through toxicmitophagy. |
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