Pacritinib
Cat. No. :YN340191
CAS No. :937272-79-2
86-020-82000279
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order@ubiochem.com| Product Name: | Pacritinib |
| CAS NO.: | 937272-79-2 |
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| Molecular Weight: | 472.58 |
| Molecular Formula: | C₂₈H₃₂N₄O₃ |
| SMILES: | C1(COC/C=C/COCC2=C(OCCN3CCCC3)C=CC4=C2)=CC=CC(C5=N/C(NC=C5)=N4)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Pacritinib is a potent inhibitor of both wild-typeJAK2(IC50=23nM) and JAK2V617Fmutant (IC50=19nM). Pacritinib also inhibitsFLT3(IC50=22nM) and its mutantFLT3D835Y(IC50=6nM). |
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