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Pacritinib

Cat. No. :YN340191

  • CAS No. :937272-79-2

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    • Biological Activity
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    • Product Name:Pacritinib
      CAS NO.:937272-79-2
      Chemical Name:
      Synonyms:
      Molecular Weight:472.58
      Molecular Formula:C₂₈H₃₂N₄O₃
      SMILES:C1(COC/C=C/COCC2=C(OCCN3CCCC3)C=CC4=C2)=CC=CC(C5=N/C(NC=C5)=N4)=C1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Pacritinib is a potent inhibitor of both wild-typeJAK2(IC50=23nM)  and JAK2V617Fmutant (IC50=19nM). Pacritinib also inhibitsFLT3(IC50=22nM)  and  its mutantFLT3D835Y(IC50=6nM).
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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