Ilginatinib maleate
Cat. No. :YN340220
CAS No. :1354799-87-3
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Product Name: | Ilginatinib maleate |
CAS NO.: | 1354799-87-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 505.50 |
Molecular Formula: | C₂₅H₂₄FN₇O₄ |
SMILES: | CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1.O=C(O)/C=CC(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailableJAK2inhibitor, with an IC50 of 0.72nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33nM), JAK3 (IC50, 39nM), and Tyk2 (IC50, 22nM). |
IC50&Target: | |
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References: |
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