FM-479
Cat. No. :YN340124
CAS No. :2226521-64-6
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order@ubiochem.com| Product Name: | FM-479 |
| CAS NO.: | 2226521-64-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 442.51 |
| Molecular Formula: | C₂₅H₂₆N₆O₂ |
| SMILES: | O=C(N(C)C)/C(C#N)=C/C1=CC=C(C2=NC3=CN=C(N(C)C=C4)C4=C3N2C5CCCCC5)O1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | FM-479 is thenegative controlof FM-381 (HY-102046) and has no activity on JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor ofJAK3targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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