AMG-47a
Cat. No. :YN340209
CAS No. :882663-88-9
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order@ubiochem.com| Product Name: | AMG-47a |
| CAS NO.: | 882663-88-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 535.56 |
| Molecular Formula: | C₂₉H₂₈F₃N₅O₂ |
| SMILES: | O=C(NC1=CC=CC(C(F)(F)F)=C1)C2=CC=C(C)C(C3=CC4=CN=C(NCCN5CCOCC5)N=C4C=C3)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of interleukin-2 (IL-2) in mice. |
| IC50&Target: | |
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