Pyridone 6
Cat. No. :YN340157
CAS No. :457081-03-7
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Product Name: | Pyridone 6 |
CAS NO.: | 457081-03-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 309.34 |
Molecular Formula: | C₁₈H₁₆FN₃O |
SMILES: | FC1=CC2=C(C(NC=C3)=O)C3=C(N=C(C(C)(C)C)N4)C4=C2C=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Pyridone 6 is apan-JAKinhibitor, which potently inhibits the JAK kinase family, with IC50s of 1nM forJAK2 and TYK2, 5nM forJAK3, and 15nM forJAK1, while displaying significantly weaker affinities (130nM to >10 mM) for other protein tyrosine kinases. |
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