Ilginatinib
Cat. No. :YN340221
CAS No. :1239358-86-1
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Product Name: | Ilginatinib |
CAS NO.: | 1239358-86-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 389.43 |
Molecular Formula: | C₂₁H₂₀FN₇ |
SMILES: | CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Ilginatinib (NS-018) is a highly active and orally bioavailableJAK2inhibitor, with an IC50 of 0.72nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33nM), JAK3 (IC50, 39nM), and Tyk2 (IC50, 22nM). |
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