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Ilginatinib

Cat. No. :YN340221

  • CAS No. :1239358-86-1

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    • Products Infomation
    • Biological Activity
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    • Product Name:Ilginatinib
      CAS NO.:1239358-86-1
      Chemical Name:
      Synonyms:
      Molecular Weight:389.43
      Molecular Formula:C₂₁H₂₀FN₇
      SMILES:CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Ilginatinib (NS-018) is a highly active and orally bioavailableJAK2inhibitor, with an IC50 of 0.72nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33nM), JAK3 (IC50, 39nM), and Tyk2 (IC50, 22nM).
      IC50&Target:
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      In Vivo:
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