PF-06826647
Cat. No. :YN340107
CAS No. :2127109-84-4
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order@ubiochem.com| Product Name: | PF-06826647 |
| CAS NO.: | 2127109-84-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 383.41 |
| Molecular Formula: | C₂₀H₁₇N₉ |
| SMILES: | N#CC[C@@]1(N2N=CC(C3=NC(C4=CN(C)N=C4)=CN5C3=CC=N5)=C2)C[C@@H](C#N)C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PF-06826647 is an orally active and selectiveTYK2inhibitor (IC50=17nM), which binds to TYK2 catalytically active JH1 domain. PF-06826647 displays selectivity for TYK2 over JAK1 (IC50=383nM) and JAK2 (74nM). PF-06826647 can be used for the research of psoriasis, ulcerative colitis, and hidradenitis suppurativa. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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