TyK2-IN-2
Cat. No. :YN340026
CAS No. :2098466-94-3
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Product Name: | TyK2-IN-2 |
CAS NO.: | 2098466-94-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 310.35 |
Molecular Formula: | C₁₆H₁₈N₆O |
SMILES: | CNC1=CC(NC2=CC(C)=CC(C)=C2)=NN3C1=NC=C3C(N)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | TyK2-IN-2 (Compoud 18) is a potent and selectiveTYK2inhibitor with IC50s of 7nM, 0.1μM and 0.05μM forTYK2 JH2,IL-23 and IFNα, respectively. TyK2-IN-2 also inhibitsphosphodiesterase 4 (PDE4)with an IC50 of 62nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases. |
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