RGB-286638 free base
Cat. No. :YN340176
CAS No. :784210-88-4
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order@ubiochem.com| Product Name: | RGB-286638 free base |
| CAS NO.: | 784210-88-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 545.63 |
| Molecular Formula: | C₂₉H₃₅N₇O₄ |
| SMILES: | O=C(NN1CCOCC1)NC2=CC=CC(C3=C4C(C5=CC=C(CN6CCN(CCOC)CC6)C=C5)=NN3)=C2C4=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | RGB-286638 is aCDKinhibitor that inhibits the kinase activity ofcyclin T1-CDK9,cyclin B1-CDK1,cyclin E-CDK2,cyclin D1-CDK4,cyclin E-CDK3, and p35-CDK5with IC50s of 1, 2, 3, 4, 5 and 5nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54nM. |
| IC50&Target: | |
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| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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