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Metabolic Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN482880 Baohuoside VII 119730-89-1

    Baohuoside VII is a flavonoid isolated fromHerba Epimedii, with anti-osteoporosis activities.

  • YN320663 Dexloxiglumide 119817-90-2

    Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8).

  • YN321836 HCGRP-(8-37) 119911-68-1

    HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist ofCGRP receptor.

  • YN320173 RG-12525 120128-20-3

    RG-12525 is a a specific, competitive and orally effective antagonist of thepeptidoleukotrienes,LTC4,LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of ...

  • YN373418 Chrysophanol triglucoside 120181-07-9

    Chrysophanol triglucoside is an anthraquinone isolated fromCassia obtusifolia, inhibitsprotein tyrosine phosphatases 1B (PTP1B) and α-glucosidasewith IC50s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has t...

  • YN482971 Bernardioside A 121368-52-3

    Bernardioside A is a triterpenoid saponin isolated fromBellis bernardii.

  • YN1720009 Heptasaccharide Glc4Xyl3 121591-98-8

    Heptasaccharide Glc4Xyl3, a covalent inhibitor ofendo-xyloglucanases, is used for the identification and analysis of diverse xyloglucan-active enzymes in nature.

  • YN482947 Gymnemic acid I 122168-40-5

    Gymnemic acid I is a bioactive triterpene saponin found inGymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress.

  • YN360615 Rosiglitazone 122320-73-4

    Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and...

  • YN483828 Amylin, amide, human 122384-88-7

    Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying...

  • YN320176 Deriglidole 122830-14-2

    Deriglidole is a peripheraladrenoceptorantagonist with a high affinity for α2-adrenoceptors.

  • YN372563 Candoxatril 123122-55-4

    C and oxatril is a neutral endopeptidase (NEP) inhibitor.

  • YN270412 Clofarabine 123318-82-1

    Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

  • YN270400 Etomoxir 124083-20-1

    Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

  • YN483805 Asp-Asp-Asp-Asp-Asp 124219-00-7

    Asp-Asp-Asp-Asp-Asp is a peptide consists of 5 Asp.

  • YN483885 Amylin, amide, rat 124447-81-0

    Amylin, amide, rat is a potent and high affinity lig and ofAmylin receptor AMY1 and AMY3receptors and variably of AMY2 receptors; binding studies are generally used for the latter receptor.

  • YN370179 YM17E 124900-72-7

    YM17E is an inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), with IC50 of 44nM in rabbit liver microsomes in vitro.

  • YN483476 Glycyroside 125310-04-5

    Glycyroside is a isoflavone diglycoside isolated fromGlycyrrhiza eurycarpaP. C. Li.

  • YN484116 Acetyl-Hirudin (54-65) (sulf... 125441-00-1

    Acetyl-Hirudin (54-65) (sulfated) binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex...

  • YN360489 Sibutramine hydrochloride mon... 125494-59-9

    Sibutramine hydrochloride monohydrate is a novel5-HT(serotonin) and noradrenaline reuptake inhibitor (SNRI). TheIC50for Sibutramine block of voltage-gated K+channel (KV)4.3is 17.3μM.

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