YN420319 SAMS 125911-68-4

SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).

YN370209 Atorvastatin lactone 125995-03-1

Atorvastatin lactone is a prodrug form of atorvastatin. Atorvastatin is an orally active3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)reductase inhibitor.

YN330559 11-oxo-mogroside V 126105-11-1

11-oxo-mogroside V is a natural sweetener, isolated from the fruits ofMomordica grosvenori, exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2-,H2O2 and *OH) withEC50of ...

YN251672 Ginsenoside Rg4 126223-28-7

Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves ofPanax ginsengC. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including ant...

YN483814 Peptide YY (PYY) (3-36),... 126339-09-1

Peptide YY (PYY) (3-36), human is a gut hormone peptide that acts as aY2 receptoragonist to reduce appetite.

YN370102 SR12813 126411-39-0

SR-12813 is a pregnane X receptor (PXR) agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM.

YN360415 KN-62 127191-97-3

KN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 μM also a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). It is selective for C...

YN320128 BRL 37344 sodium 127299-93-8

BRL 37344 sodium (BRL 37344A) is a specificβ3-adrenergic receptoragonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice.

YN320574 Zamifenacin 127308-82-1

Zamifenacin (UK-76654) is a potent gut-selectivemuscarinic M3 receptorantagonist. Zamifenacin significantly reduces colonic motility in irritable bowel syndrome.

YN320332 Zamifenacin fumarate 127308-98-9

Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selectivemuscarinic M3 receptorantagonist. Zamifenacin significantly reduces colonic motility in irritable bowel syndrome.

YN483761 PACAP (1-27), human, ovin... 127317-03-7

Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is a potent PACAP receptor antagonist.

YN483069 Maohuoside A 128988-55-6

Maohuoside A, a single compound isolated from theE. koreanumthat potently promotes osteogenesis. Maohuoside A enhances the osteogenesis of bone marrow-derived mesenchymal stem cells via bone morphogenetic protein (BMP) and MAPK...

YN483132 Aurantio-obtusin β-D-glucos... 129025-96-3

Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds ofCassia tora), is a glucoside of aurantio-obtusin.

YN373092 Lobetyolin 129277-38-9

Lobetyolin, a bioactive compound, is derived fromCodonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidaseinhibiting activities. Lobetyolin also induces the apoptosis via the inhibition ofASCT2-medi...

YN322003 [Tyr(P)4] Angiotensin II 129785-85-9

[Tyr(P)4] Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

YN470019 MC 976 129831-99-8

MC 976 is a Vitamin D3 derivative.

YN374307 Phytic acid potassium 129832-03-7

Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.

YN482468 Mogroside III 130567-83-8

Mogroside III, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

YN483944 Pneumadin, rat 130918-90-0

Pneumadin, rat (PNM) is a decapeptide, which possess a potent stimulating effect on arginine-vasopressin (AVP) release. Pneumadin, rat (PNM) exerts a marked antidiuretic effect in animals with functional AVP system.

YN481538 NB-598 131060-14-5

NB-598 is a potent and competitive inhibitor ofsqualene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway.