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Metabolic Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN481206 (3R,5S)-Atorvastatin sodium 131275-93-9

    (3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation...

  • YN470034 Paricalcitol 131918-61-1

    Paricalcitol is avitamin D receptoragonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.

  • YN360300 5-Hydroxylansoprazole 131926-98-2

    5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastricproton-pumpinhibitor and is effective in the treat...

  • YN310251 Bisindolylmaleimide I 133052-90-1

    Bisindolylmaleimide I (GF109203X) is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold select...

  • YN1720034 Avexitide 133514-43-9

    Avexitide (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.

  • YN483487 Soyasaponin Ac 133882-74-3

    Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.

  • YN372824 Atorvastatin 134523-00-5

    Atorvastatin is an orally activeHMG-CoAreductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39μM and 2.39μM, respectiv...

  • YN372431 Atorvastatin hemicalcium salt 134523-03-8

    Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.

  • YN440442 GIP (1-30) amide, porcine 134846-93-8

    GIP (1-30) amide, porcine is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42).

  • YN483079 6''-O-Acetylglycitin 134859-96-4

    6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind.

  • YN372636 Meluadrine tartrate 134865-37-5

    Meluadrine tartrate is an endogenous metabolite.

  • YN481424 Repaglinide 135062-02-1

    Repaglinide is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes.

  • YN321129 Strontium Ranelate 135459-87-9

    Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate also can activate thecalcium-sensing receptor (...

  • YN484121 Amylin (8-37), human 135702-23-7

    Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human can direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms...

  • YN483956 IGF-I (24-41) 135861-49-3

    IGF-I (24-41) is amino acids 24 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, a...

  • YN370314 Fidarestat 136087-85-9

    Fidarestat (SNK 860) is an inhibitor ofaldose reductase, with IC50s of 26nM, 33μM, and 1.8μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabeti...

  • YN320196 Lintitript 136381-85-6

    Lintitript (SR 27897) is a highly potent, selective, orally active, competitive and non-peptidecholecystokinin (CCK1) receptorantagonist with an EC50 of 6nM and a Ki of 0.2nM. Lintitript displays > 33-fold selectivity more s...

  • YN370175 RP 70676 136609-26-2

    RP 70676 is a potent inhibitor ofACAT, with IC50 of 25 and 44nM for rat and rabbit ACAT.

  • YN480044 RP 73163 Racemate 136609-53-5

    RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potentACATinhibitor, with cholesterol lowering activity.

  • YN481539 NB-598 hydrochloride 136719-25-0

    NB-598 hydrochloride is a potent and competitive inhibitor ofsqualene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway.

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