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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN330526 Nobiletin 478-01-3

    Nobiletin, a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities.

  • YN380230 Linarin 480-36-4

    Linarin (Buddleoside), isolated from the flower extract ofMentha arvensis, shows selective dose dependent inhibitory effect on acetylcholinesterase (AChE).

  • YN330645 α-Spinasterol 481-18-5

    α-Spinasterol, isolated fromSpinacia oleracea, has antibacterial activity. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive eff...

  • YN360921 Imperatorin 482-44-0

    Imperatorin, a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.

  • YN251461 Isoimperatorin 482-45-1

    Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.

  • YN321707 Rotundine 483-14-7

    Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

  • YN321732 Jatrorrhizine hydroxide 483-43-2

    Jatrorrhizine hydroxide is an alkaloid isolated fromCoptis chinensiswith neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor ofAChE(IC50=872...

  • YN380254 Osthenol 484-14-0

    Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots ofAngelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A(hMAO-A)inhibitor (Ki=0.26 µM). Osthenol potently inhibits recomb...

  • YN330639 Okanin 484-76-4

    Okanin, effective constituent of the flower teaCoreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of theTLR4/NF-κBsignaling pathways.

  • YN360984 Coclaurine 486-39-5

    Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated fromSarcopetalum harveyanum. Coclaurine is anicotinic acetylcholine receptor (nAChRs)antagonist.

  • YN482820 Hypaphorine 487-58-1

    Hypaphorine is an indole alkaloid isolated fromPisolithus tinctorius, and with neurological and glucose-lowering effects in rodents.

  • YN482888 Kainic acid 487-79-6

    Kainic acid is a potent agonist atexcitatory amino acid receptorsubtypes in the CNS.

  • YN374104 Scyllo-Inositol 488-59-5

    scyllo-Inositol is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm.

  • YN373326 D-Arabitol 488-82-4

    D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

  • YN251941 4(3H)-Quinazolinone 491-36-1

    Some 4-quinazolinone derivatives have antiplatelet activity.

  • YN372213 Biochanin A 491-80-5

    Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 &muM.

  • YN361085 (+)-Sparteine 492-08-0

    Inhibition of human CYP2D6 expressed in Escherichia coli JM109

  • YN360051 Kynurenic acid 492-27-3

    Kynurenic acid, a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist It proved to be an antagonist at NMDA, kainate and AMPA receptors.

  • YN360875 Anabasine 494-52-0

    Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component intobacco(Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces d...

  • YN372667 Coumaran 496-16-2

    Coumaran (2,3-Dihydrobenzofuran) is anacetylcholinesterase (AChE)inhibitor isolated from leaves ofL. camara. Coumaran can be used as a biopesticide.

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